林美华-材料与化学学院
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化学系 | Department Of Chemistry
 

林美华

林美华 研究员 硕士生导师                        

中国地质大学(武汉) 材料与化学学院

湖北省武汉市洪山区鲁磨路388号学海楼421

话:027-67885201

Emaillinmh@cug.edu.cn

教育与研究经历

2017-至今,  中国地质大学(武汉)材料与化学学院(研究员,硕士生导师)

2015-2017  马里兰大学帕克分校,博士后 (合作导师:Zhihong Nie

2010-2015  中国科学院大学上海应用物理研究所,博士学位(导师:樊春海研究员)

2015/3-2015/9 厦门大学,交流学习 (导师:杨朝勇教授)

2006-2010  福州大学,化学基地班,学士学位(导师:杨黄浩教授)

学术成果

主要从事DNA纳米结构自组装设计及其在生物传感、生物成像的应用,无机纳米材料合成、组装及在生物中的应用。目前为止,在国内外知名期刊上发表论文10余篇,其中包括Nature Protocols, Advance Materials, Angewandte, Analytical Chemistry等杂志,总引用500余次。

获奖与荣誉

  1. 中国科学院优秀博士学位论文(2016

  2. 中科院院长优秀奖(2015)、中国科学院/北京市优秀毕业生 (2015)

  3. 博士研究生国家奖学金

承担项目与课题

1.       DNA纳米结构探针设计及其在单细胞内双信号检测多种生物分子的应用(中央高校基本科研业务费专项资金)

代表性成果

https://www.researchgate.net/profile/Meihua_Lin

1.      Meihua Lin#, Ping Song, Guobao Zhou, Xiaolei Zuo,* Ali Aldalbahi, Xiaoding Lou, Jiye Shi, Chunhai Fan Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA nanostructure-based universal biosensing platform. Nature Protocols. 2016, 1244-1263.

2.      Meihua Lin#, Hao Pei, Fan Yang, Chunhai Fan,* and Xiaolei Zuo* Applications of Gold Nanoparticles in the Detection and Identification of Infectious Diseases and Biothreats. Advanced Materials. 2013, 25, 3490-3496.

3.      Meihua Lin#, Jingjing Wang, Guobao Zhou, Jianbang Wang, Na Wu, Jianxin Lu, Jimin Gao, Xiaoqing Chen, Jiye Shi, Xiaolei Zuo*, and Chunhai Fan* Programmable engineering of biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection. Angewandte Chemie International Edition. 2015, 54, 2151–2155.(Very Important Paper)

4.      Meihua Lin#, Yanli Wen#, Lanying Li, Hao Pei, Gang Liu, Haiyun Song, Xiaolei Zuo,Chunhai Fan, and Qing Huang*Target-Responsive, DNA Nanostructure- Based E‑DNA Sensor for microRNA Analysis. Analytical Chemistry. 2014, 86, 22852288.

5.      Zhilei Ge#, Meihua Lin#, Ping Wang, Hao Pei, Juan Yan, Jiye Shi, Qing Huang, Dannong He, Chunhai Fan, and Xiaolei Zuo* Hybridization Chain Reaction Amplication of MicroRNA Detection with a Tetrahedral DNA Nanostructure-Based Electrochemical Biosensor. Analytical Chemistry. 2014, 86, 21242130. (ESI高被引)

6.      Jiaoyun Xia, Meihua Lin, Xiaolei Zuo, Shao Su, Lihua Wang, Wei Huang, chunhai Fan, and Qing Huang* Metal Ion-Mediated Assembly of DNA Nanostructures for Cascade Fluorescence Resonance Energy Transfer-Based Fingerprint Analysis. Analytical Chemistry. 2014, 86, 7084-7087.

7.      Guobao Zhou, Meihua Lin, Ping Song, Xiaoqing Chen,* Jie Chao, Lianhui Wang, Qing Huang, Wei Huang, Chunhai Fan, and Xiaolei Zuo* Multivalent Capture and Detection of Cancer Cells with DNA Nanostructured Biosensors and Multibranched Hybridization Chain Reaction Amplifi cation. Analytical Chemistry. 2014, 86, 7843-7848.

8.      Alireza Abi, Meihua Lin, Hao Pei, Chunhai Fan,* Elena E. Ferapontova,* and Xiaolei Zuo* Electrochemical Switching with 3D DNA Tetrahedral Nanostructures Self-Assembled at Gold Electrodes. ACS Applied Materials & Interfaces.2014, 6, 8928-8931.

9.      Yanli Wen, Hao Pei, Ye Shen, Junjie Xi, Meihua Lin, Na Lu, Xizhong Shen, Jiong Li, and Chunhai Fan* DNA Nanostructure-based Interfacial engineering for PCR-free ultrasensitive electro- chemical analysis of microRNA. SCIENTIFIC REPORTS. 2014, 2, 867-871.

10.   Chunhua Lu, Juan Li, Meihua Lin, Yiwei Wang, Huanghao Yang,* Xi Chen, and Guonan Chen Amplified Aptamer-Based Assay through Catalytic Recycling of the Analyte. Angewandte Chemie International Edition. 2010, 49, 8454-8457.

11.   Xiaoying Lin, Yi Liu, Meihua Lin, Qian Zhang, Zhihong Nie* Synthesis of circular and triangular gold nanorings with tunable optical properties. Chemical Communications. 2017, 53, 10765 -10767.