师资情况
 
 
 
 
当前位置: 首页 > 师资情况 > 化学系 > 正文
 
化学系 | Department Of Chemistry
 

娄筱叮

娄筱叮

博士,教授,博导,中国地质大学(武汉)材料与化学学院

联系方式:louxiaoding@cug.edu.cn

课题组网站:http://anxiang15.xm45.host.35.com/

教育经历(按时间倒序排序):

2007/9 - 2012/6,武汉大学,有机化学,博士,

导师:李振教授

2004/9 - 2007/6,武汉大学,化学基地班,交流生

2003/9 - 2004/6,湖北工程学院,化学教育学,学士

工作经历(科研与学术工作经历,按时间倒序排序):

2017/1-至今,中国地质大学(武汉),材料与化学学院,教授

2016/4-2016/10,加州大学圣塔芭芭拉分校,物理系,访问学者,合作导师:Alan J. Heeger 教授(2000年诺贝尔奖得主)

2014/11-2016/12,华中科技大学,化学与化工学院,副教授

2013/8-2014/10,华中科技大学,化学与化工学院,讲师

2012/8-2013/7,香港科技大学,高分子系,ResearchAssociate,合作导师:唐本忠院士

主持或参加科研项目及人才计划项目情况(按时间倒序排序):

1、           国家自然科学基金优秀青年基金,21722507、化学生物传感、2018/01-2020/12130万元、在研、主持。

2、           浙江省自然科学基金一般项目,LY18B050002、基于多标志物联合技术的微纳米器件的构筑及其在乳腺癌早期检测中的应用、2018/01-2020/1210万、在研、主持。

3、           国家自然科学基金面上项目,21574048、亲疏水可调DNA-AIE高分子复合探针的构建及其传感性能研究、2016/01-2019/1265万元、在研、主持。

4、           国家自然科学基金青年项目,21405054微纳米限域空间内聚集诱导发光分子的组装行为在生物/化学传感器中的应用2015/01-2017/1225万元、在研、主持。

5、           湖北省自然科学基金面上项目,2014CFB1012聚集诱导发光分子在微纳米孔道中传感性能的研究2014/01-2015/123万元、结题、主持。

6、           国家重点研发计划重大科学仪器设备开发专项,2016YFF01008002017/01-2019/12基于微流控高通量芯片的新型高灵敏传感系统开发及应用100万元、在研、子课题负责人。

国家优秀青年科学基金获得者,湖北省“楚天学者计划”楚天学子,湖北省青联十三届委员会常委,湖北省青年科学协会委员。

研究领域为生命分析化学,在国际核心期刊Chem. Soc. Rev., Angew. Chem. Int. Ed., Adv. Mater.Nat. Comm.,Nat. Prot.,上发表/接收SCI论文72篇(影响因子大于5的论文52篇,第一或通讯作者文章46篇)。相关研究成果已被国际知名刊物引用1400余次,H因子为23

研究成果列表(2015-今)

1.       Duan, Ruixue, Lou, Xiaoding(*) and Xia, Fan(*),The development of nanostructure assisted isothermal amplification in biosensors, Chemical Society Reviews, 2016, 45, 1738-1749. IF=38.618

2.       Cheng, Yong(#), Dai, Jun(#), Sun, Chunli(#), Liu, Rui, Zhai, Tianyou, Lou, Xiaoding(*) and Xia, Fan(*), Intracellular H2O2-responsive AIEgen with peroxidase-mediated catalysis for inflammatory cell selective imaging and inhibition,Angewandte Chemie International Edition, 2018, 57, 3123-3127. IF=11.994;

3.       Gao, Pengcheng, Hu, Lintong, Liu, Nannan, Yang, Zekun, Lou, Xiaoding(*), Zhai, Tianyou(*), Li, Huiqiao, and Xia, Fan(*),Functional “janus” annulus in confined channel, Advanced Materials, 2016, 28, 460-465. IF=19.791

4.       Cheng, Yong, Sun, Chunli, Ou, Xiaowen, Liu, Bifeng, Lou, Xiaoding(*), and Xia, Fan(*),Dual-targeted peptide-conjugated multifunctional fluorescent probe with AIEgen for efficient nucleus-specific imaging and long-term tracing of cancer cells. Chemical Science, 2017, 8, 4571-4578. IF=8.668

5.       Chen, Yanxia, Min, Xuehong, Zhang, Xiqi, Zhang, Feilong, Lu, Simeng, Xu, Li-Ping(*), Lou, Xiaoding(*), Xia, Fan, Zhang, Xueji(*), Wang, Shutao, AIE-based superwettable microchips for evaporation and aggregation induced fluorescence enhancement biosensing Biosensors and Bioelectronics, 2018, 111, 124-130. IF=7.780

6.       Xu, Xuemei, Zhao, Wei, Gao, Pengcheng, Li, Huiqing, Feng, Guang, Zhao, Zujin, Lou, Xiaoding(*),Coordination of the electrical and optical signals revealing nanochannels with an “onion-like” gating mechanism and its sensing application, NPG Asia Materials, 2016,2016,8, e234. IF=9.157

7.       Gao, Zhongfeng(#), Sann, Ei Ei(#), Lou, Xiaoding(#), Liu, Renyi, Dai, Jun(*), Zuo, Xiaolei, Xia, Fan(*) and Jiang Lei,Naked eye point-of-care testing platform based on pH-responsive superwetting surface: toward non-invasive detection of glucose,NPG Asia Materials, 2018, DOI 10.1038/s41427-018-0024-7; IF=9.157

8.       Chang, Zhengfeng, Jing, Lingmin, Chen, Bin, Zhang, Mengshi, Liu, Junjie, Ye, Yanchun,Lou, Xiaoding(*), Zhao, Zujin(*), Liu, Bin(*),Wang, Jinliang(*), Tang, Ben Zhong, Rational design of asymmetric red fluorescent probes for live cell imaging with high AIE effect and large two-photon absorption cross section by tuneable terminal group, Chemical Science, 2016, 7, 4527-4536. IF=8.668

9.       Zi Long(#), Shenshan Zhan(#),Pengcheng Gao, Yongqian Wang, Xiaoding Lou(*), Fan Xia(*), Recent advances in solid nano-pore/channel analysis. Analytical Chemistry, 2018, 90, 577-588. IF=6.320

10.    Jia, Yongmei(#), Gao, Pengcheng(#), Zhuang, Yuan(#), Miao, Mao, Lou, Xiaoding(*), Xia, Fan, Facile probe design: fluorescent amphiphilic nucleic acid probes without quencher providing telomerase activity Imaging inside living cells, Analytical Chemistry, 2016, 88, 6621-6626. IF=6.320

11.    Zhang,Xiaojin, Lou, Xiaoding(*),Xia, Fan(*), Advances in the detection of telomerase activity using isothermal amplification, Theranostics, 2017,7, 1847-1862. IF=8.712

12.    Ou, Xiaowen, Lou, Xiaoding(*), Xia, Fan(*), A highly sensitive DNA-AIEgen-based “turn-on” fluorescence chemosensor for amplification analysis of Hg2+ ions in real samples and living cells, Science China Chemistry, 2017, 60, 663-669. IF=4.132

13.    Min,Xuehong, Xia,Lei, Zhuang,Yuan, Wang,Xudong, Du, Jie, Zhang,Xiaojin, Lou,Xiaoding(*), Xia, Fan(*), An AIEgens and exonuclease III aided quadratic amplification assay for detecting and cellular imaging of telomerase activity, Science Bulletin, 2017, 62,997-1003, IF=4.000

14.    Zhuang,Yuan(#), Shang,Chunli(#), Lou,Xiaoding(*), Xia, Fan(*), Construction of AIEgens-based bioprobe with two fluorescent signals for enhanced monitor of extracellular and intracellular telomerase activity, Analytical Chemistry,2017, 89, 2073-2079. IF=6.320

15.    Ou, Xiaowen, Wei, Benmei, Zhang, Zhenyu, Zhang, Mengshi, Zhuang, Yuan, Gao, Pengcheng(*), Lou, Xiaoding(*), Xia, Fan, Tang, Ben Zhong, Detection of UVA/UVC-induced damage of p53 fragment by rolling circle amplification with AIEgens, Analyst, 2016, 141,4394-4399. IF=3.885

16.    Ou, Xiaowen, Hong, Fan, Zhang, Zhenyu, Cheng, Yong, Zhao, Zujin, Gao, Pengcheng, Lou, Xiaoding(*), Xia, Fan, Wang, Shutao, A highly sensitive and facile graphene oxide-based nucleic acid probe: label-free detection of telomerase activity in cancer patient's urine using AIEgens, Biosensors and Bioelectronics, 2016, 141, 4394-4399. IF=7.780

17.    Liu,Nannan(#), Li, Cao(#), Zhang, Tianchi, Hou, Ruizuo, Xiong, Zhiping, Li, Zeyong, Wei, Benmei, Yang, Zekun, Gao, Pengcheng(*), Lou, Xiaoding(*), Zhang, Xianzheng, Guo, Wei, Xia, Fan, Fabrication of "plug and play" channels with dual responses by host-guest interactions, Small, 2017,13(1600287):1~6. IF=8.643

18.    Lou, Xiaoding, Zhao, Zujin(*), Tang, Ben Zhong(*), Organic dots based on AIEgens for two-photon fluorescence bioimaging, Small, 2016, 12, 6430-6450. IF=8.643

19.    Lou, Xiaoding, Zhang, Mengshi, Zhao, Zujin, Min, Xuehong, Hakeem, Abdul, Huang, Fujian, Gao, Pengcheng, Xia, Fan (*), Tang, Ben Zhong, A photostable AIE fluorogen for lysosome-targetable imaging of living cells,Journal of Materials Chemistry B, 2016, 4, 5412-5417. IF= 4.543

20.    Cheng, Yong, Huang, Fujian, Min, Xuehong, Gao, Pengcheng, Zhang, Tianchi, Li, Xinchun, Liu, Bifeng, Hong, Yuning, Lou, Xiaoding(*), Xia, Fan(*), Protease-responsive prodrug with aggregation-induced emission probe for controlled drug delivery and drug release tracking in living cells, Analytical Chemistry, 2016, 88, 8913-8919. IF=6.320

21.    Min, Xuehong(#), Zhang, Mengshi(#), Huang, Fujian, Lou, Xiaoding(*), Xia, Fan, Live cell microRNA imaging using exonuclease III-aided recycling amplification based on AIEgens, ACS Applied Materials & Interfaces, 2016, 8, 8998-9003. IF=7.504

22.    Zhuang, Yuan(#), Xu, Qi(#), Huang, Fujian, Gao, Pengcheng, Zhao, Zujin, Lou, Xiaoding(*), Xia, Fan, Ratiometric fluorescent bioprobe for highly reproducible detection of telomerase in bloody urines of bladder cancer patients, ACS Sensors, 2016,1, 572-578

23.    Xu, Xuemei, Hou, Ruizuo, Gao, Pengcheng, Miao, Mao, Lou, Xiaoding(*), Liu, Bifeng, Xia, Fan, Highly robust nanopore-based dual-signal-output ion detection system for achieving three successive calibration curves, Analytical Chemistry, 2016, 88, 2386-2391. IF=6.320

24.    Zhuang, Yuan,Huang, Fujian,Xu, Qi,Zhang, Mengshi, Lou, Xiaoding(*), Xia, Fan,Facile, Fast-responsive and photostable imaging of telomerase activity in living cells with a fluorescence turn-on manner,AnalyticalChemistry, 2016, 88, 3289-3294. IF=6.320

25.    Hakeem, Abdul,Zahid, Fouzia,Duan, Ruixue,Asif, Muhammad,Zhang, Tianchi,Zhang, Zhenyu,Cheng, Yong,Lou, Xiaoding(*),Xia, Fan(*), Cellulose conjugated FITC-labelled mesoporous silica nanoparticles: intracellular accumulation and stimuli responsive doxorubicin release,Nanoscale, 2016, 8, 5089-5097. IF=7.367

26.    Liu, Nannan, Hou, Ruizuo, Gao, Pengcheng, Lou, Xiaoding(*), Fan Xia, Sensitive Zn2+ sensor based on biofunctionalized nanopores by combination of DNAzyme and DNA supersandwich structures, Analyst, 2016, 141, 3626-3629. IF=3.885

27.    Zhuang, Yuan, Zhang Mengshi, Chen Bin, Duan Ruixue, Min Xuehong, Zhang Zhenyu, Zheng Fuxin, Liang Huageng, Zhao Zujin, Lou Xiaoding(*), Xia Fan, Quencher group induced high specificity detection of telomerase in clear and bloody urines by AIEgens, Analytical Chemistry, 2015, 87, 9487-9493.IF=6.320

28.    Lou, Xiaoding(#),Zhuang, Yuan(#), Zuo, Xiaolei(#), Jia, Yongmei, Hong, Yuning, Min, Xuehong, Zhang, Zhenyu, Xu, Xuemei, Liu, Nannan, Xia, Fan(*), Tang, Ben Zhong, Real-time, quantitative lighting-up detection of telomerase in urines of bladder cancer patients by AIEgens, Analytical Chemistry, 2015, 87, 6822-6827.IF=6.320

29.    Min, Xuehong(#),Zhuang, Yuan(#), Zhang, Zhenyu, Jia, Yongmei,  Zheng, Fuxin, Cheng, Yong, Tang, Ben Zhong, Lou, Xiaoding(*), Xia, Fan, Lab in a tube: sensitive detection of microRNAs in urines samples from bladder cancer patients using a single-label DNA probe with AIEgens, ACS Applied Materials & Interfaces,2015, 7, 16813-16818.IF=7.504

30.    Jia, Yongmei(#), Zuo, Xiaolei(#), Lou, Xiaoding(#), Miao, Mao, Cheng, Yong, Min, Xuehong, Li, Xinchun, Xia, Fan(*), Rational designed bipolar, conjugated polymer-DNA composite beacon for the sensitive detection of proteins and ions, Analytical Chemistry, 2015,87, 3890-3894. IF=6.320